Description

tert-Butyl 3-(4-Formylphenoxy)Azetidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a versatile azetidine ring and a reactive formyl group. This compound is critical for the synthesis of complex bioactive molecules, particularly in medicinal chemistry and drug discovery. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for constructing novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its reactive aldehyde functionality for further derivatization.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker component in the design of heterobifunctional molecules for targeted protein degradation.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific custom synthesis projects.
• Academic Research: A valuable reagent for universities and research institutes exploring new synthetic methodologies and bioactive compound libraries.

Basic Information

Product Name	tert-Butyl 3-(4-Formylphenoxy)Azetidine-1-Carboxylate
CAS No.	696588-36-0
Molecular Formula	C15H19NO4
Molecular Weight	277.32 g/mol
Synonyms	1-Boc-3-(4-formylphenoxy)azetidine; tert-Butyl 3-(4-formylphenoxy)azetidine-1-carboxylate; 3-(4-Formylphenoxy)azetidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-(4-formylphenoxy)azetidine; Azetidine-1-carboxylic acid, 3-(4-formylphenoxy)-, 1,1-dimethylethyl ester; Boc-3-(4-formylphenoxy)azetidine; 696588-36-0
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(4-Formylphenoxy)Azetidine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specification results. We support cGMP compliance for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.