Description

1-(Bromomethyl)-4-Nitro-2-(Trifluoromethyl)Benzene is a versatile and high-value aromatic building block containing bromomethyl, nitro, and trifluoromethyl functional groups. This compound is critical for advanced organic synthesis, enabling the introduction of multiple reactive handles for constructing complex molecules. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethyl or nitro-substituted aromatic scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Acts as a monomer or functionalization agent in the development of advanced polymers and organic electronic materials.
• Cross-Coupling Reactions: The bromomethyl group makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck).
• Nucleophilic Substitution: The reactive benzyl bromide moiety allows for facile functionalization with a wide range of nucleophiles.

Basic Information

Product Name	1-(Bromomethyl)-4-Nitro-2-(Trifluoromethyl)Benzene
CAS No.	694499-22-4
Molecular Formula	C9H5BrF3NO2
Molecular Weight	296.04 g/mol
Synonyms	4-Nitro-2-(trifluoromethyl)benzyl bromide; 2-(Trifluoromethyl)-4-nitrobenzyl bromide; α-Bromo-4-nitro-α,α,α-trifluoro-o-xylene; (4-Nitro-2-(trifluoromethyl)phenyl)methyl bromide; 1-Bromomethyl-4-nitro-2-trifluoromethylbenzene; Benzene, 1-(bromomethyl)-4-nitro-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 1-(Bromomethyl)-4-Nitro-2-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, assay, and impurity profiles to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere if possible and opened with minimal exposure to ambient air and light.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.