Description

1,8-Naphthyridine-3-Carboxylic Acid, 1-(3-Boronophenyl)-1,4-Dihydro-4-Oxo-, 3-Ethyl Ester is a sophisticated boron-containing heterocyclic compound that serves as a critical building block in advanced organic synthesis. This molecule is valued for its unique structural features, combining a naphthyridine core with a boronic acid ester functional group, which enables precise cross-coupling reactions and molecular assembly. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting enzymes or receptors where the boron moiety can be utilized in Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a monomer or functional unit in the creation of advanced organic electronic materials, such as OLEDs or sensors, due to its conjugated system.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying biological processes, where the boronic ester can act as a recognition or labeling handle.
• Organic Synthesis Building Block: A versatile reagent for constructing complex polycyclic architectures in academic and industrial research settings.
• Catalyst Ligand Precursor: Potential use in the development of novel ligand systems for transition metal catalysis.

Basic Information

Product Name	1,8-Naphthyridine-3-Carboxylic Acid, 1-(3-Boronophenyl)-1,4-Dihydro-4-Oxo-, 3-Ethyl Ester
CAS No.	694489-60-6
Molecular Formula	C₁₈H₁₅BN₂O₄
Molecular Weight	334.14 g/mol
Synonyms	3-Ethyl 1-(3-boronophenyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate; 1-(3-Boronophenyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid 3-Ethyl Ester; 1,8-Naphthyridine-3-carboxylic acid, 1-(3-boronophenyl)-1,4-dihydro-4-oxo-, ethyl ester; Ethyl 1-(3-boronophenyl)-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate; CAS 694489-60-6
EINECS	Contact for details

Quality Control

Our production of 1,8-Naphthyridine-3-Carboxylic Acid, 1-(3-Boronophenyl)-1,4-Dihydro-4-Oxo-, 3-Ethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.