Description

3-Hydroxy-2,3-Dimethylbutan-2-Yl Hydrogen (2,6-Dimethylpyridin-3-Yl)Boronate is a specialized organoboron compound, specifically a boronic ester derivative, that serves as a critical intermediate in modern synthetic chemistry. Its value lies in its role as a versatile building block for constructing complex molecular architectures, particularly in the development of pharmaceuticals and advanced materials. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, reliable intermediates for cross-coupling reactions and other sophisticated synthetic transformations.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents and herbicides, where the boronate moiety enables efficient carbon-carbon bond formation.
• Material Science Research: Serves as a building block for creating organic electronic materials, ligands for catalysis, and novel polymers with tailored properties.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for studying biological processes and diagnostics.
• Catalyst & Ligand Preparation: Utilized in the preparation of sophisticated ligands for transition metal catalysts used in asymmetric synthesis.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	3-Hydroxy-2,3-Dimethylbutan-2-Yl Hydrogen (2,6-Dimethylpyridin-3-Yl)Boronate
CAS No.	693774-10-6
Molecular Formula	C13H22BNO3
Molecular Weight	251.13 g/mol
Synonyms	2,6-Dimethyl-3-pyridinylboronic acid, 2,3-dimethyl-2-hydroxybutyl ester; (2,6-Dimethylpyridin-3-yl)boronic acid 3-hydroxy-2,3-dimethylbutan-2-yl ester; 3-Hydroxy-2,3-dimethyl-2-butyl (2,6-dimethyl-3-pyridinyl)boronate; Pinanediol-type boronate ester derivative; Organoboron ester intermediate.
EINECS	Contact for details

Quality Control

Every batch of 3-Hydroxy-2,3-Dimethylbutan-2-Yl Hydrogen (2,6-Dimethylpyridin-3-Yl)Boronate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including NMR (1H, 11B, 13C), HPLC, and GC analysis, to ensure identity, purity, and consistency meet the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid or crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Typical 97-99%)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.