Description

[3-(1-Methylethyl)-1H-Indazol-4-Yl] Boronic Acid is a high-purity, functionalized boronic acid derivative, a critical building block in modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecules through reliable cross-coupling reactions. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its indazole core for biological activity.
• Material Science Research: Serves as a building block for creating organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Biology & Proteomics: Employed in the development of chemical probes and inhibitors for target identification and validation studies.
• Catalyst Ligand Precursor: Can be utilized to synthesize novel ligands for transition metal catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	[3-(1-Methylethyl)-1H-Indazol-4-Yl] Boronic Acid
CAS No.	693285-69-7
Molecular Formula	C10H13BN2O2
Molecular Weight	204.04 g/mol
Synonyms	4-(Isopropyl)-1H-indazol-3-ylboronic acid; 3-Isopropyl-1H-indazol-4-ylboronic acid; (3-Isopropyl-1H-indazol-4-yl)boronic acid; B-[3-(1-Methylethyl)-1H-indazol-4-yl]boronic acid; 693285-69-7; Boronic acid, B-[3-(1-methylethyl)-1H-indazol-4-yl]-; 3-Isopropyl-4-borono-1H-indazole
EINECS	Contact for details

Quality Control

Our [3-(1-Methylethyl)-1H-Indazol-4-Yl] Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.