Description

5-Bromo-2,3-Dihydrobenzo[B]Furan-7-Boronic Acid is a high-value, multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing the benzofuran scaffold.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific halogenated heterocyclic structures.
• Material Science: Building block for creating organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where its planar structure and bromine substituent are advantageous.
• Chemical Research & Development: Versatile reagent in academic and industrial R&D labs for constructing complex organic molecules via palladium-catalyzed cross-coupling reactions.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Library Synthesis for High-Throughput Screening: Employed in combinatorial chemistry to generate diverse compound libraries for biological activity screening.

Basic Information

Product Name	5-Bromo-2,3-Dihydrobenzo[B]Furan-7-Boronic Acid
CAS No.	690632-72-5
Molecular Formula	C8H8BBrO3
Molecular Weight	242.87 g/mol
Synonyms	5-Bromo-2,3-dihydro-7-benzofuranboronic acid; 7-Borono-5-bromo-2,3-dihydrobenzofuran; 5-Bromo-2,3-dihydrobenzofuran-7-boronic acid; (5-Bromo-2,3-dihydrobenzofuran-7-yl)boronic acid; 5-Bromo-2,3-dihydrobenzo[b]furan-7-ylboronic acid; 690632-72-5; B- (5-Bromo-2,3-dihydrobenzo[b]furan-7-yl) boronic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,3-Dihydrobenzo[B]Furan-7-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance in sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.