Description

2-Oxa-5-Azabicyclo[2.2.1]Heptane-5-Acetaldehyde,(1S,4S)-(9Ci) is a high-purity, chiral bicyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. Pharmaceutical R&D and fine chemical manufacturers need this specific stereoisomer to ensure the precise stereochemistry required for target biological activity and process efficiency.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for developing novel chiral ligands and organocatalysts.
• Peptidomimetic & Constrained Scaffold Synthesis: Used to introduce rigid, bicyclic motifs that mimic peptide secondary structures in medicinal chemistry.
• Agrochemical Research: Employed in the development of enantiomerically pure agrochemicals with enhanced efficacy and environmental profile.
• Academic & Process Chemistry: A valuable tool for methodological studies in organic synthesis and scale-up process development.

Basic Information

Product Name	2-Oxa-5-Azabicyclo[2.2.1]Heptane-5-Acetaldehyde,(1S,4S)-(9Ci)
CAS No.	688736-81-4
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	(1S,4S)-2-Oxa-5-azabicyclo[2.2.1]heptane-5-acetaldehyde; (1S,4S)-5-(2-Oxoethyl)-2-oxa-5-azabicyclo[2.2.1]heptane; (1S,4S)-5-Azabicyclo[2.2.1]heptane-2-one, 5-(2-oxoethyl)-, 2-oxide (9CI); Bicyclic amino aldehyde derivative; Chiral 2-oxa-5-azabicycloheptane acetaldehyde.
EINECS	Contact for details

Quality Control

Our 2-Oxa-5-Azabicyclo[2.2.1]Heptane-5-Acetaldehyde,(1S,4S)-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and advanced synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1S,4S)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.