Description

2-(Benzyloxy)-1-Bromo-3-Nitrobenzene is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. This compound is valued for its unique substitution pattern, which provides distinct reactivity for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as drug discovery and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those requiring complex aromatic ether and nitro-substituted structures.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogen and nitro functional groups for further derivatization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the development of organic electronic materials, dyes, and photoactive compounds due to its electron-withdrawing nitro group and aromatic backbone.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form biaryl and other conjugated systems.
• Academic & Industrial R&D: A versatile reagent for methodological studies and exploring new synthetic pathways in organic chemistry laboratories worldwide.

Basic Information

Product Name	2-(Benzyloxy)-1-Bromo-3-Nitrobenzene
CAS No.	688363-79-3
Molecular Formula	C13H10BrNO3
Molecular Weight	308.13 g/mol
Synonyms	1-Bromo-2-(benzyloxy)-3-nitrobenzene; 2-Benzyloxy-1-bromo-3-nitrobenzene; 3-Nitro-2-benzyloxybromobenzene; Benzene, 1-bromo-2-(phenylmethoxy)-3-nitro-; o-Benzyloxy-m-bromo-nitrobenzene; (2-Benzyloxy-3-nitrophenyl)bromide
EINECS	Contact for details

Quality Control

Our 2-(Benzyloxy)-1-Bromo-3-Nitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.