Description

4-Iodobenzoyltrifluoroacetone is a specialized fluorinated β-diketone building block, distinguished by its iodine and trifluoromethyl substituents. This compound is valued for its unique reactivity profile, enabling the synthesis of complex molecules with enhanced properties for advanced material and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting fluorinated compounds.
• Ligand Precursor: Serves as a starting material for the synthesis of chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Employed in the discovery and synthesis of new fluorinated pesticides and herbicides, leveraging the bioactivity-enhancing properties of fluorine.
• Material Science: Used in the preparation of advanced polymers and organic electronic materials where the iodine moiety allows for further functionalization via cross-coupling reactions.
• Chemical Synthesis: Acts as a versatile building block in organic synthesis for constructing complex heterocycles and fluorinated molecular architectures.

Basic Information

Product Name	4-Iodobenzoyltrifluoroacetone
CAS No.	685892-12-0
Molecular Formula	C10H6F3IO2
Molecular Weight	342.05 g/mol
Synonyms	1-(4-Iodophenyl)-4,4,4-trifluoro-1,3-butanedione; 4-Iodobenzoyltrifluoroacetone; 4'-Iodo-2,2,2-trifluoroacetophenone; 1-(4-Iodobenzoyl)-3,3,3-trifluoroacetone; p-Iodobenzoyltrifluoroacetone; 4-Iodo-α,α,α-trifluoroacetophenone; TFIBA
EINECS	Contact for details

Quality Control

Our 4-Iodobenzoyltrifluoroacetone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is sensitive to strong alkalis and fluorides; keep away from incompatible substances.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.