Description

2,3-Dihydro-1-Benzofuran-7-Boronic Acid is a high-purity boronic acid derivative and a valuable synthetic intermediate in modern organic chemistry. Its primary value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable building blocks for drug discovery, catalyst development, and the synthesis of functional organic molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing the dihydrobenzofuran scaffold.
• Suzuki-Miyaura Cross-Coupling Reagent: Serves as a versatile boronic acid partner for palladium-catalyzed carbon-carbon bond formation, essential for creating complex molecular architectures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands used in homogeneous catalysis.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological processes and target identification.

Basic Information

Product Name	2,3-Dihydro-1-Benzofuran-7-Boronic Acid
CAS No.	685514-61-8
Molecular Formula	C8H9BO3
Molecular Weight	163.97 g/mol
Synonyms	7-Borono-2,3-dihydro-1-benzofuran; 2,3-Dihydrobenzofuran-7-boronic acid; 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1-benzofuran (Pinacol ester precursor); Dihydrobenzofuran-7-boronic Acid; 1-Benzofuran-7-boronic acid, 2,3-dihydro-; 2,3-Dihydrobenzo[b]furan-7-ylboronic acid
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1-Benzofuran-7-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.