Description

4-Isoquinolineboronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound matters for its critical role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. Pharmaceutical, agrochemical, and advanced materials researchers need it for the efficient synthesis of novel isoquinoline-containing compounds, which are valuable scaffolds in drug discovery and functional material development.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing potential drug candidates containing the isoquinoline pharmacophore, targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new active ingredients for crop protection agents through structure-activity relationship (SAR) studies.
• Material Science: Enables the creation of organic electronic materials, such as OLED emitters or charge-transport layers, via controlled cross-coupling.
• Chemical Biology: Serves as a versatile handle for bioconjugation or in the synthesis of molecular probes and imaging agents.
• Catalyst Ligand Synthesis: A precursor for constructing sophisticated ligand frameworks used in homogeneous catalysis.
• Academic & Process R&D: Employed in methodological development and scale-up studies for efficient route scouting in fine chemical synthesis.

Basic Information

Product Name	4-Isoquinolineboronic Acid Pinacol Ester
CAS No.	685103-98-4
Molecular Formula	C₁₅H₁₈BNO₂
Molecular Weight	255.12 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinoline; 4-Isoquinolylboronic Acid Pinacol Ester; 4-(Pinacolboryl)isoquinoline; 4-Isoquinolineboronic Acid, Pinacol Ester; 4-Isoquinolineboronic Acid Neopentyl Glycol Ester (common alternative); 4-Boronisoquinoline Pinacol Ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-isoquinoline
EINECS	Contact for details

Quality Control

Our 4-Isoquinolineboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency and traceability for your research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic (moisture-sensitive) nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.