Description

2-Cyclopenten-1-One, 4,5-Dihydroxy-2-(1E)-1-Propenyl-, (4S,5S)- (9Ci) is a high-purity, stereochemically defined chiral building block with significant synthetic utility. This compound is valued for its functionalized cyclopentenone core, which serves as a versatile intermediate in the synthesis of complex natural products and bioactive molecules. It is primarily sought after by research institutions and pharmaceutical development companies engaged in asymmetric synthesis and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of prostaglandins, cyclopentanoid natural products, and other bioactive compounds with defined stereochemistry.
• Asymmetric Synthesis: Used as a precursor in stereoselective reactions, including Michael additions, cycloadditions, and ring-opening transformations to construct complex molecular architectures.
• Medicinal Chemistry Research: Employed in the discovery and development of new chemical entities, particularly for probing structure-activity relationships (SAR) around the cyclopentenone scaffold.
• Fine Chemical Production: Serves as a starting material for the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Industrial R&D: Utilized in methodological studies and process development for novel synthetic routes in organic chemistry.

Basic Information

Product Name	2-Cyclopenten-1-One, 4,5-Dihydroxy-2-(1E)-1-Propenyl-, (4S,5S)- (9Ci)
CAS No.	683276-29-1
Molecular Formula	C8H10O3
Molecular Weight	154.16 g/mol
Synonyms	(4S,5S)-4,5-Dihydroxy-2-[(1E)-1-propenyl]-2-cyclopenten-1-one; (4S,5S)-4,5-Dihydroxy-2-[(E)-1-propenyl]cyclopent-2-en-1-one; 4,5-Dihydroxy-2-[(1E)-1-propenyl]-2-cyclopenten-1-one, (4S,5S)-; (4S,5S)-Dihydroxypropenylcyclopentenone; Chiral Dihydroxypropenylcyclopentenone; (4S,5S)-Isomer of 4,5-Dihydroxy-2-(1-propenyl)-2-cyclopenten-1-one
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥95% (by HPLC) and stringent control of enantiomeric excess. Certificates of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and residual solvent levels are available upon request. Our quality system supports development and cGMP manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.