Description

2-(2-Bromoacetyl)Benzonitrile is a versatile and highly reactive chemical building block, primarily used as a key intermediate in advanced organic synthesis. Its value lies in the strategic combination of a reactive bromoacetyl group and a nitrile functionality, enabling the construction of complex heterocyclic and pharmaceutical scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates, particularly those containing benzofuran, indole, or quinazoline core structures.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactivity to create complex bioactive molecules.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers and functional organic materials.
• Chemical Biology & Proteomics: Employed as an affinity probe or labeling reagent due to its electrophilic bromoacetyl group, which can react with thiol groups in proteins.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic pathways.
• Dye & Pigment Intermediate: Used in the synthesis of specialized colorants and photostable pigments.

Basic Information

Product Name	2-(2-Bromoacetyl)Benzonitrile
CAS No.	683274-86-4
Molecular Formula	C9H6BrNO
Molecular Weight	224.06 g/mol
Synonyms	2-Bromoacetylbenzonitrile; 2-Bromo-1-(2-cyanophenyl)ethanone; 2-Cyanophenacyl Bromide; α-Bromo-2-cyanophenacyl Bromide; 1-(2-Cyanophenyl)-2-bromoethanone; (2-Cyanophenyl)(bromo)methanone; Bromomethyl 2-cyanophenyl ketone
EINECS	Contact for details

Quality Control

Our 2-(2-Bromoacetyl)Benzonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. Our quality management system is designed to meet the stringent requirements of GMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.