Description

2-Bromo-1-(5-Chloro-2-Methoxy-4-Methyl-3-Nitro-Phenyl)Ethanone is a specialized halogenated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring bromo, chloro, nitro, and methoxy substituents, makes it a versatile precursor for constructing complex heterocyclic systems and functionalized aromatic compounds. This high-purity intermediate is primarily utilized by research institutions and pharmaceutical development teams engaged in the creation of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the multi-step synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Used in the development and optimization of novel herbicides, fungicides, and pesticides, leveraging its reactive halogen and nitro groups.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce complex aromatic motifs.
• Material Science Research: Acts as a precursor for synthesizing specialized monomers or ligands for advanced polymers and coordination complexes.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions.

Basic Information

Product Name	2-Bromo-1-(5-Chloro-2-Methoxy-4-Methyl-3-Nitro-Phenyl)Ethanone
CAS No.	683274-75-1
Molecular Formula	C10H9BrClNO4
Molecular Weight	322.54 g/mol
Synonyms	2-Bromo-1-(5-chloro-2-methoxy-4-methyl-3-nitrophenyl)ethan-1-one; 2-Bromo-1-(5-chloro-2-methoxy-4-methyl-3-nitrophenyl)ethanone; α-Bromo-5'-chloro-2'-methoxy-4'-methyl-3'-nitroacetophenone; 5-Chloro-2-methoxy-4-methyl-3-nitro-α-bromoacetophenone; 683274-75-1; Bromo(5-chloro-2-methoxy-4-methyl-3-nitrophenyl)methanone (incorrect but common search variant)
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-1-(5-Chloro-2-Methoxy-4-Methyl-3-Nitro-Phenyl)Ethanone is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Single impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.