Description

5-Methoxy-1H-Indole-2-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic organic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel indole-based drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that require complex heterocyclic structures.
• Material Science: Building block for creating organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology: Employed in the synthesis of molecular probes and bioconjugates for studying biological pathways and protein interactions.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	5-Methoxy-1H-Indole-2-Boronic Acid Pinacol Ester
CAS No.	683229-62-1
Molecular Formula	C₁₅H₂₀BNO₃
Molecular Weight	273.14 g/mol
Synonyms	5-Methoxy-1H-indol-2-ylboronic acid pinacol ester; 2-(5-Methoxy-1H-indol-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Methoxyindole-2-boronic acid pinacol ester; 5-Methoxy-2-indoleboronic acid pinacol ester; 683229-62-1; BRN 8237565
EINECS	Contact for details

Quality Control

Our 5-Methoxy-1H-Indole-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.