Description

Cyclopentanecarbonitrile, 2-Hydroxy-1-(2-Propenyl)-, (1R,2S)- (9Ci) is a high-purity, chiral organic compound featuring a cyclopentane ring substituted with a nitrile and a hydroxyl group, with an allyl chain at the stereogenic center. This specific stereochemistry makes it a critical chiral building block for the synthesis of complex, biologically active molecules. It is primarily needed by pharmaceutical R&D and fine chemical synthesis teams for developing new active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Utilized as a precursor for constructing complex molecular architectures with high enantiomeric purity in fine chemical and process chemistry.
• Agrochemical Research: Serves as a building block for developing new, stereospecific pesticides and herbicides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands and organocatalysts for asymmetric catalytic reactions.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic synthesis and stereochemistry at research institutions and corporate labs.
• Custom Synthesis Projects: Employed in contract manufacturing and development organizations (CDMOs) for bespoke, multi-step synthetic routes.

Basic Information

Product Name	Cyclopentanecarbonitrile, 2-Hydroxy-1-(2-Propenyl)-, (1R,2S)- (9Ci)
CAS No.	682746-85-6
Molecular Formula	C9H13NO
Molecular Weight	151.21 g/mol
Synonyms	(1R,2S)-2-Hydroxy-1-(prop-2-en-1-yl)cyclopentane-1-carbonitrile; (1R,2S)-1-Allyl-2-hydroxycyclopentanecarbonitrile; (1R,2S)-2-Hydroxy-1-(2-propenyl)cyclopentanecarbonitrile; (1R,2S)-1-(Allyl)-2-hydroxycyclopentanecarbonitrile; 2-Hydroxy-1-(2-propenyl)cyclopentanecarbonitrile, (1R,2S)-; Cyclopentanecarbonitrile, 2-hydroxy-1-(2-propenyl)-, (1R,2S)-rel-; A chiral cyclopentane nitrile derivative
EINECS	Contact for details

Quality Control

Our chiral intermediates are produced under strict quality management systems. Each batch of Cyclopentanecarbonitrile, 2-Hydroxy-1-(2-Propenyl)-, (1R,2S)- (9Ci) undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification and identity confirmation by spectroscopic methods. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, chiral purity, and impurity profiles to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.