Description

4-(Trifluoromethoxy)Cinnamic Aldehyde is a high-value fluorinated aromatic aldehyde building block. This compound matters for its unique trifluoromethoxy substituent, which imparts enhanced lipophilicity, metabolic stability, and electronic properties to final molecules. It is primarily needed by R&D and production chemists in the pharmaceutical and agrochemical industries for synthesizing novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in areas requiring fluorinated motifs for improved bioavailability and target binding.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved performance and durability.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, condensations, and as a precursor for corresponding acids, alcohols, and other derivatives in fine chemical manufacturing.
• Flavor & Fragrance Research: Used in the synthesis of novel aromatic compounds for specialty fragrance and flavor applications.
• Polymer & Material Science: Incorporated as a monomer or modifier to create polymers with specific thermal, chemical, or surface properties.

Basic Information

Product Name	4-(Trifluoromethoxy)Cinnamic Aldehyde
CAS No.	681484-59-3
Molecular Formula	C10H7F3O2
Molecular Weight	216.16 g/mol
Synonyms	3-[4-(Trifluoromethoxy)phenyl]prop-2-enal; 4-(Trifluoromethoxy)benzeneacrolein; (E)-3-(4-(Trifluoromethoxy)phenyl)acrylaldehyde; p-(Trifluoromethoxy)cinnamaldehyde; 4-(Trifluoromethoxy)cinnamaldehyde; 4-Trifluoromethoxycinnamic aldehyde; (E)-4-(Trifluoromethoxy)cinnamaldehyde
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)Cinnamic Aldehyde is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.