Description

4H-Furo[2,3-B]Pyran-3-Ol, Hexahydro-2-Methyl-, (2R,3R,3As,7Ar)- (9Ci) is a high-purity, stereochemically defined chiral compound with the CAS number 681283-11-4. This molecule serves as a sophisticated synthetic intermediate and building block for advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and life science industries for the synthesis of novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Used in the development of new, stereoselective pesticides and herbicides where specific chirality impacts biological activity.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to construct complex molecular architectures.
• Natural Product Analog Synthesis: Core structure for synthesizing analogs of natural products containing fused furan and pyran rings.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of high-value fine chemicals.
• Chemical Reference Standard: Used as a high-purity analytical standard for method development and quality control in regulatory submissions.

Basic Information

Item	Details
Product Name	4H-Furo[2,3-B]Pyran-3-Ol, Hexahydro-2-Methyl-, (2R,3R,3As,7Ar)- (9Ci)
CAS No.	681283-11-4
Molecular Formula	C9H14O3
Molecular Weight	170.21 g/mol
Synonyms	(2R,3R,3aS,7aR)-Hexahydro-2-methyl-4H-furo[2,3-b]pyran-3-ol; Hexahydro-2-methyl-4H-furo[2,3-b]pyran-3-ol, (2R,3R,3aS,7aR)-; 4H-Furo[2,3-b]pyran-3-ol, hexahydro-2-methyl-, (2R,3R,3aS,7aR)-; (3R,3aS,7aR)-Hexahydro-2-methyl-4H-furo[2,3-b]pyran-3-ol; 681283-11-4; Furopyranol derivative; Chiral furopyranol building block
EINECS	Contact for details

Quality Control

Our production of 4H-Furo[2,3-B]Pyran-3-Ol, Hexahydro-2-Methyl-, (2R,3R,3As,7Ar)- (9Ci) adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization, including chiral purity verification by HPLC, to ensure identity, strength, and stereochemical integrity. Certificates of Analysis (COA) with full traceability are provided, supporting development work under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Any single impurity ≤ 1.0%; Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.