Description

Cyclopentaneacetic Acid, -α-,-α--Difluoro-1-Hydroxy-3-Methyl- (9Ci) is a high-purity fluorinated organic building block of significant interest in advanced synthetic chemistry. This compound is valued for its unique molecular architecture, which incorporates both fluorine atoms and a hydroxyl group on a cyclopentane backbone, enabling precise modifications to molecular properties. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key fluorinated synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the introduction of fluorine atoms can improve biological activity and environmental persistence profiles.
• Material Science Research: Serves as a specialized monomer or precursor for developing novel fluorinated polymers with specific thermal, chemical, or surface properties.
• Ligand and Catalyst Development: Employed in the synthesis of complex, chiral ligands for asymmetric catalysis and organometallic chemistry applications.
• Chemical Biology Probes: Utilized as a building block for creating labeled compounds or molecular probes used in biochemical and diagnostic research.

Basic Information

Product Name	Cyclopentaneacetic Acid, -α-,-α--Difluoro-1-Hydroxy-3-Methyl- (9Ci)
CAS No.	681240-29-9
Molecular Formula	C8H12F2O3
Molecular Weight	194.18 g/mol
Synonyms	2-(2,2-Difluoro-1-hydroxy-3-methylcyclopentyl)acetic acid; α,α-Difluoro-1-hydroxy-3-methylcyclopentaneacetic acid; 1-Hydroxy-3-methyl-α,α-difluorocyclopentaneacetic acid; (2,2-Difluoro-1-hydroxy-3-methylcyclopentyl)acetic acid; 681240-29-9; Cyclopentaneacetic acid, α,α-difluoro-1-hydroxy-3-methyl-; Difluorinated Cyclopentane Hydroxy Acid Derivative
EINECS	Contact for details

Quality Control

Our production of Cyclopentaneacetic Acid, -α-,-α--Difluoro-1-Hydroxy-3-Methyl- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.