Description

Diethyl (2-Chloro-6-Fluorobenzyl)Phosphonate is a high-purity organophosphorus compound, specifically a phosphonate ester, serving as a critical synthetic intermediate. Its value lies in its role as a versatile building block for constructing complex molecules, particularly in the synthesis of active pharmaceutical ingredients (APIs) and advanced agrochemicals. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for scale-up and production.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, insecticides, and fungicides, leveraging the fluorine and chlorine substituents for enhanced biological activity.
• Ligand and Catalyst Precursor: Serves as a precursor for phosphonate-based ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of flame retardants, plasticizers, and other functional materials where phosphonate chemistry is required.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Diethyl (2-Chloro-6-Fluorobenzyl)Phosphonate
CAS No.	680214-57-7
Molecular Formula	C11H15ClFO3P
Molecular Weight	279.66 g/mol
Synonyms	Diethyl (2-Chloro-6-fluorobenzyl)phosphonate; (2-Chloro-6-fluorobenzyl)phosphonic Acid Diethyl Ester; Phosphonic Acid, P-[(2-Chloro-6-fluorophenyl)methyl]-, Diethyl Ester; Diethyl (2-Chloro-6-fluorophenylmethyl)phosphonate; Diethyl [(2-Chloro-6-fluorophenyl)methyl]phosphonate; 680214-57-7; (2-Chloro-6-fluorobenzyl)phosphonate Diethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl (2-Chloro-6-Fluorobenzyl)Phosphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and fluorides. The container must be kept tightly closed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.