Description

5-(Benzyloxy)-2-Bromobenzotrifluoride is a high-value halogenated aromatic building block characterized by its benzyl-protected phenol and bromo-trifluoromethyl substitution pattern. This compound matters for its versatility in facilitating complex molecular construction, particularly in the synthesis of advanced pharmaceutical intermediates and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethylated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the benzyloxy and bromo groups serve as handles for further functionalization.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in cross-coupling catalysis and other transition metal-mediated reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers where fluorine substitution modulates electronic properties.
• Chemical Biology Probes: Useful for constructing molecular probes and tags due to the reactive bromine atom and stable trifluoromethyl group.

Basic Information

Item	Details
Product Name	5-(Benzyloxy)-2-Bromobenzotrifluoride
CAS No.	678164-30-2
Molecular Formula	C14H10BrF3O
Molecular Weight	331.13 g/mol
Synonyms	2-Bromo-5-(benzyloxy)benzotrifluoride; 1-Benzyloxy-4-bromo-2-(trifluoromethyl)benzene; 2-Bromo-α,α,α-trifluoro-5-(phenylmethoxy)toluene; 5-Benzyloxy-2-bromo-α,α,α-trifluorotoluene; 5-(Benzyloxy)-2-bromo-α,α,α-trifluorotoluene; 2-Bromo-5-(phenylmethoxy)benzotrifluoride; 5-(Benzyloxy)-2-bromobenzotrifluoride
EINECS	Contact for details

Quality Control

Our 5-(Benzyloxy)-2-Bromobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.