Description

Cyclohexanone, 2-Hydroxy-3-(1-Methoxy-1-Methylethyl)-6-Methyl-, (2R,3S,6S)-Rel- (9Ci) is a high-purity, stereochemically defined derivative of cyclohexanone, valued for its role as a sophisticated chiral building block in advanced organic synthesis. Its complex structure, featuring multiple stereocenters and a protected hydroxyl group, makes it a critical intermediate for constructing molecules with precise three-dimensional architecture. This compound is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to synthesize active ingredients requiring specific stereochemistry for optimal efficacy and safety.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in the development of antiviral, anti-inflammatory, or central nervous system (CNS) active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where the specific spatial orientation of the molecule is crucial for biological activity.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development and study of new asymmetric catalytic reactions.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances that require high stereochemical purity.
• Academic & Industrial R&D: A critical tool for chemists in both academic institutions and corporate R&D labs exploring novel synthetic pathways and molecular architectures.

Basic Information

Product Name	Cyclohexanone, 2-Hydroxy-3-(1-Methoxy-1-Methylethyl)-6-Methyl-, (2R,3S,6S)-Rel- (9Ci)
CAS No.	678159-63-2
Molecular Formula	C12H22O3
Molecular Weight	214.30 g/mol
Synonyms	rel-(2R,3S,6S)-2-Hydroxy-3-(1-methoxy-1-methylethyl)-6-methylcyclohexanone; (2R,3S,6S)-2-Hydroxy-3-(2-methoxypropan-2-yl)-6-methylcyclohexanone; 2-Hydroxy-3-(1-methoxy-1-methylethyl)-6-methylcyclohexanone (rel-(2R,3S,6S)-); Cyclohexanone, 2-hydroxy-3-(1-methoxy-1-methylethyl)-6-methyl-, (2R,3S,6S)-rel-; Chiral Cyclohexanone Derivative; MOM-protected hydroxy cyclohexanone derivative
EINECS	Contact for details

Quality Control

Our production of this advanced chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high stereochemical purity, which is critical for downstream synthesis. Quality is verified through comprehensive analytical techniques including HPLC, chiral GC, and NMR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, enantiomeric/excess, and key physical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral GC/HPLC)	≥ 99.0% e.e. (for specified isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.