Description

2-Cyclopenten-1-One, 4,5-Dihydroxy-4-[(1S)-1-Hydroxyethyl]-, (4R,5S)- (9Ci) CAS NO 677751-81-4 is a high-purity, stereochemically defined chiral building block and synthetic intermediate. Its complex polyhydroxylated cyclopentenone structure makes it a valuable precursor for the synthesis of biologically active natural products and novel pharmaceutical compounds. This material is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries engaged in asymmetric synthesis and complex molecule construction.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of prostaglandins, nucleoside analogs, and other complex bioactive molecules.
• Agrochemical Research: Used in the development of novel, stereospecific pesticides and plant growth regulators.
• Fine Chemical Synthesis: Serves as a versatile building block for creating specialty chemicals, flavors, and fragrances with specific stereochemistry.
• Academic & R&D: A critical reagent in organic chemistry research for methodology development and total synthesis projects.
• Catalyst Ligand Precursor: Potential use in the synthesis of chiral ligands for asymmetric catalysis.

Basic Information

Product Name	2-Cyclopenten-1-One, 4,5-Dihydroxy-4-[(1S)-1-Hydroxyethyl]-, (4R,5S)- (9Ci)
CAS No.	677751-81-4
Molecular Formula	C7H10O4
Molecular Weight	158.15 g/mol
Synonyms	(4R,5S)-4,5-Dihydroxy-4-[(1S)-1-hydroxyethyl]cyclopent-2-en-1-one; (4R,5S)-4,5-Dihydroxy-4-[(1S)-1-hydroxyethyl]-2-cyclopenten-1-one; 4,5-Dihydroxy-4-[(1S)-1-hydroxyethyl]-2-cyclopenten-1-one, (4R,5S)-; 677751-81-4; (1S,4R,5S)-4,5-Dihydroxy-4-(1-hydroxyethyl)cyclopent-2-en-1-one
EINECS	Contact for details

Quality Control

Our 2-Cyclopenten-1-One, 4,5-Dihydroxy-4-[(1S)-1-Hydroxyethyl]-, (4R,5S)- (9Ci) is manufactured under strict quality control protocols to ensure high chemical and stereochemical purity, essential for sensitive synthetic applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and easily oxidized nature. Allow the container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.