Description

2-Bromo-1-(4-Chlorothiophen-2-Yl)Ethanone is a high-purity halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile electrophilic reagent, enabling the introduction of key functional groups into complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactive bromoacetyl moiety.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials with unique electronic properties.
• Chemical Biology Probe Development: Employed to create molecular probes for studying enzyme mechanisms and protein interactions due to its electrophilic character.
• Organic Synthesis Building Block: Facilitates various name reactions, including nucleophilic substitutions and cyclizations, to construct complex thiophene-containing heterocycles.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP or research-grade conditions.

Basic Information

Product Name	2-Bromo-1-(4-Chlorothiophen-2-Yl)Ethanone
CAS No.	677007-73-7
Molecular Formula	C6H4BrClOS
Molecular Weight	239.52 g/mol
Synonyms	2-Bromo-1-(4-chloro-2-thienyl)ethanone; 4-Chloro-2-bromoacetylthiophene; 2-Bromo-4'-chloro-2'-thienyl ketone; 4-Chloro-2-thienyl bromomethyl ketone; α-Bromo-4-chloro-2-thienyl methyl ketone; 1-(4-Chloro-2-thienyl)-2-bromoethanone; Bromo(4-chloro-2-thienyl)methanone; 677007-73-7
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(4-Chlorothiophen-2-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent lot-to-lot performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.