Description

2-Indoleboronic Acid CAS NO 676578-20-4 is a high-purity boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who are developing novel heterocyclic compounds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex indole-based molecules in drug discovery and API synthesis.
• Suzuki-Miyaura Cross-Coupling Reactions: Used as a versatile boronic acid coupling partner to introduce the indole moiety into biaryl and heterobiaryl systems.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and insecticides with indole scaffolds.
• Material Science: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & R&D Laboratories: A fundamental reagent for methodological development in organic synthesis and medicinal chemistry.

Basic Information

Product Name	2-Indoleboronic Acid
CAS No.	676578-20-4
Molecular Formula	C8H8BNO2
Molecular Weight	160.97 g/mol
Synonyms	1H-Indole-2-boronic acid; 2-Boronobenzofuran; Indol-2-ylboronic acid; 2-Indolylboronic acid; Boronic acid, B-(1H-indol-2-yl)-; 2-Indoleboronic acid pinacol ester (common derivative); B-(1H-Indol-2-yl)boronic acid
EINECS	Contact for details

Quality Control

Our 2-Indoleboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.