Description

2-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole is a valuable, highly functionalized heterocyclic building block featuring a protected boronic ester group. This compound is essential for modern synthetic chemistry, enabling the construction of complex molecular architectures through efficient cross-coupling reactions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing pyrrole or indole scaffolds.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products by introducing the functionalized pyrrole moiety into target molecules.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and emissive layer components in display and lighting technologies.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and organometallic complexes.
• Polymer and Material Science: Incorporated into conjugated polymers and organic semiconductors to modify electronic properties and processability.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological processes and protein interactions.

Basic Information

Product Name	2-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole
CAS No.	676501-88-5
Molecular Formula	C11H20BNO2
Molecular Weight	209.10 g/mol
Synonyms	2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methyl-1H-pyrrole; 2-Methyl-5-(pinacolatoboryl)-1H-pyrrole; 2-Methyl-5-(pinacolboranyl)-1H-pyrrole; 2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrole; 5-(Pinacolatoboryl)-2-methyl-1H-pyrrole; 1H-Pyrrole, 2-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high purity and consistent performance for critical synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to moisture during use. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.