Description

5-Cyanothiophene-2-Boronic Acid Pinacol Ester is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Material Science: Serves as a precursor for creating functional polymers, organic semiconductors, and liquid crystal materials.
• Chemical Research & Development: A versatile reagent for constructing complex thiophene-based heterocyclic scaffolds in academic and industrial R&D labs.
• Suzuki-Miyaura Cross-Coupling: The pinacol ester group offers enhanced stability, making it a preferred reagent for palladium-catalyzed coupling reactions under various conditions.

Basic Information

Product Name	5-Cyanothiophene-2-Boronic Acid Pinacol Ester
CAS No.	676501-85-2
Molecular Formula	C11H14BNO2S
Molecular Weight	235.11 g/mol
Synonyms	2-Cyano-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene; 5-Cyanothiophene-2-boronic acid pinacol ester; 2-(5-Cyanothiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Thiophene-2-boronic acid, 5-cyano-, pinacol ester; 5-Cyano-2-thienylboronic acid pinacol ester; 676501-85-2; 5-CN-Thiophene-2-Bpin
EINECS	Contact for details

Quality Control

Our 5-Cyanothiophene-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.