Description

2,2,2-Trifluoro-1-(6-Nitro-3-Indolyl)Ethanone is a specialized fluorinated indole derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a trifluoroacetyl group and a nitro-substituted indole core, makes it a valuable precursor for developing novel pharmaceuticals and agrochemicals. This high-purity intermediate is primarily sought by research institutions and chemical manufacturers engaged in the development of active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging the biological activity of the indole scaffold.
• Material Science Research: Serves as a precursor for functionalized organic molecules used in organic light-emitting diodes (OLEDs) and other electronic materials.
• Fluorination Chemistry Studies: An important reagent for studying the effects of trifluoromethyl groups on molecular properties and reactivity.
• Bioconjugation & Probe Development: Utilized in the synthesis of fluorescent probes and biochemical tags for diagnostic applications.

Basic Information

Product Name	2,2,2-Trifluoro-1-(6-Nitro-3-Indolyl)Ethanone
CAS No.	676476-90-7
Molecular Formula	C11H5F3N2O3
Molecular Weight	270.16 g/mol
Synonyms	1-(6-Nitro-1H-indol-3-yl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(6-nitro-1H-indol-3-yl)ethanone; 6-Nitro-3-trifluoroacetylindole; 3-Trifluoroacetyl-6-nitroindole; TFAN; 2,2,2-Trifluoro-1-(6-nitroindol-3-yl)ethanone; 676476-90-7
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(6-Nitro-3-Indolyl)Ethanone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.