Description

Phenyl-Phenylsulfanyl-Acetyl Chloride is a specialized organosulfur reagent featuring both phenyl and phenylsulfanyl groups attached to an acid chloride functionality. This compound is valued for its dual reactivity, serving as a versatile building block for introducing sulfur-containing motifs into target molecules. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for constructing sulfur-bridged pharmacophores in drug discovery programs, particularly for kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides where the phenylsulfanyl moiety can enhance biological activity and environmental profile.
• Material Science Precursor: Employed in the synthesis of functionalized monomers and ligands for advanced polymers and metal-organic frameworks (MOFs).
• Chemical Research: Serves as a versatile electrophile in academic and industrial R&D for exploring new C-S and C-C bond-forming reactions.
• Ligand and Catalyst Development: Useful for preparing custom sulfur-containing ligands used in asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	Phenyl-Phenylsulfanyl-Acetyl Chloride
CAS No.	676348-48-4
Molecular Formula	C14H11ClOS
Molecular Weight	262.75 g/mol
Synonyms	2-(Phenylsulfanyl)-2-phenylacetyl chloride; α-(Phenylthio)benzeneacetyl chloride; (Phenylsulfanyl)(phenyl)acetyl chloride; Phenyl(phenylthio)acetyl chloride; 2-Phenyl-2-(phenylthio)acetyl chloride; Benzeneacetic acid, α-(phenylthio)-, chloride; Phenyl-Phenylsulfanyl-Acetyl Chloride
EINECS	Contact for details

Quality Control

Our production of Phenyl-Phenylsulfanyl-Acetyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts vigorously with water, strong bases, and oxidizing agents. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.