Description

Cyclopentanecarboxylic Acid, 2-(1,1-Dimethylethyl)-5-Oxo-, Methyl Ester, (1S,2R)- (9Ci) is a high-purity, stereochemically defined chiral building block essential for advanced organic synthesis. Its value lies in its rigid cyclopentane backbone and functional groups, which are instrumental in constructing complex molecular architectures with precise spatial orientation. This compound is critically needed by pharmaceutical R&D and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where specific isomer activity is required for efficacy and environmental safety.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands and organocatalysts.
• Fine Chemical Production: Employed in the multistep synthesis of complex natural products, flavors, and fragrances.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific chiral or structural properties.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-(1,1-Dimethylethyl)-5-Oxo-, Methyl Ester, (1S,2R)- (9Ci)
CAS No.	676345-40-7
Molecular Formula	C11H18O3
Molecular Weight	198.26 g/mol
Synonyms	(1S,2R)-2-(tert-Butyl)-5-oxocyclopentanecarboxylic acid methyl ester; Methyl (1S,2R)-2-(tert-butyl)-5-oxocyclopentanecarboxylate; (1S,2R)-2-tert-Butyl-5-oxocyclopentanecarboxylic Acid Methyl Ester; tert-Butyl-oxocyclopentanecarboxylate, (1S,2R)- isomer; Chiral tert-butyl cyclopentanone carboxylate
EINECS	Contact for details

Quality Control

Our production of Cyclopentanecarboxylic Acid, 2-(1,1-Dimethylethyl)-5-Oxo-, Methyl Ester, (1S,2R)- (9Ci) adheres to stringent quality management systems to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and IR spectroscopy. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.