Description

D-Glucopyranose, 6-Deoxy-6-Fluoro-, 1-Acetate (9Ci) is a fluorinated carbohydrate derivative that serves as a crucial synthetic intermediate in advanced organic and medicinal chemistry. Its core value lies in the strategic introduction of a fluorine atom at the 6-position, which can significantly alter the biological activity, metabolic stability, and physicochemical properties of target molecules. This compound is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and life science industries for the development of novel therapeutics and biochemical probes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated nucleoside analogs, antiviral agents, and other bioactive molecules.
• Glycobiology Research: Used to study enzyme mechanisms, metabolic pathways, and as a probe in glycosylation reactions due to its modified sugar structure.
• Agrochemical Development: Serves as a precursor for creating novel fluorinated pesticides or herbicides with enhanced properties.
• Diagnostic Agent Synthesis: Potential intermediate in the production of fluorinated contrast agents or radiotracers for Positron Emission Tomography (PET) imaging.
• Chemical Biology Tool: Employed to create activity-based probes or labeled substrates for investigating carbohydrate-processing enzymes.
• Process Chemistry & Scale-up: Used in route development and optimization for the commercial manufacturing of fluorinated active pharmaceutical ingredients (APIs).

Basic Information

Product Name	D-Glucopyranose, 6-Deoxy-6-Fluoro-, 1-Acetate (9Ci)
CAS No.	674782-58-2
Molecular Formula	C8H13FO6
Molecular Weight	224.18 g/mol
Synonyms	6-Deoxy-6-fluoro-D-glucopyranose 1-acetate; 1-O-Acetyl-6-deoxy-6-fluoro-D-glucopyranose; 6-Fluoro-6-deoxy-D-glucopyranose 1-acetate; 6-Fluoro-1,2,3,4-tetra-O-acetyl-6-deoxy-D-glucopyranose (related intermediate); Fluorinated glucose acetate derivative; 6-Fluoro-D-glucose 1-acetate
EINECS	Contact for details

Quality Control

Every batch of D-Glucopyranose, 6-Deoxy-6-Fluoro-, 1-Acetate (9Ci) is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development projects. A detailed Certificate of Analysis (COA) including results for assay, purity (by HPLC), and specific impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.