Description

4-(p-Toluenesulfonylamino)Phenylboronic Acid Pinacol Ester, 97% is a high-purity organoboron building block crucial for modern synthetic chemistry. This compound matters for its role as a protected boronic acid derivative, offering enhanced stability and solubility for Suzuki-Miyaura cross-coupling reactions. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex biaryl and heterobiaryl structures.

Application

• Pharmaceutical Intermediate Synthesis: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides requiring specific biaryl motifs.
• Material Science: Employed in the creation of organic electronic materials, such as OLEDs and organic semiconductors, where precise molecular architecture is critical.
• Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the synthesis of molecular probes for diagnostic applications.
• Academic & Process R&D: A valuable reagent for methodological development in organic synthesis and scale-up process optimization.
• Ligand & Catalyst Preparation: Used in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-(p-Toluenesulfonylamino)Phenylboronic Acid Pinacol Ester, 97%
CAS No.	674776-54-6
Molecular Formula	C25H30BNO4S
Molecular Weight	451.39 g/mol
Synonyms	4-(4-Methylbenzenesulfonamido)phenylboronic acid pinacol ester; N-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-4-methylbenzenesulfonamide; 4-(p-Tolylsulfonylamino)phenylboronic acid pinacol ester; B-[4-[[(4-Methylphenyl)sulfonyl]amino]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(Tosylamino)phenylboronic acid pinacol ester; Pinacol 4-(p-toluenesulfonylamino)phenylboronate; CAS 674776-54-6
EINECS	Contact for details

Quality Control

Our 4-(p-Toluenesulfonylamino)Phenylboronic Acid Pinacol Ester is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and meet the specified 97% purity standard. Certificates of Analysis (COA) with full analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.