Description

3-(1,1-Dioxido-4-Thiomorpholinyl)-2-Azepanone (Wx619126) is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique structural features, combining a thiomorpholine dioxide moiety with an azepanone ring, which are valuable for constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and novel active ingredient discovery.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis to explore novel bioactive compounds.
• Agrochemical Development: Employed in the synthesis of novel herbicides, fungicides, or insecticides, leveraging its heterocyclic framework.
• Chemical Biology Probes: Acts as a precursor for designing molecular probes to study enzyme mechanisms or protein-ligand interactions.
• Process Chemistry & Scale-up: Used in route scouting and optimization for the efficient, scalable production of target molecules.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise chemical entity.

Basic Information

Product Name	3-(1,1-Dioxido-4-Thiomorpholinyl)-2-Azepanone (Wx619126)
CAS No.	671754-68-0
Molecular Formula	C10H18N2O3S
Molecular Weight	246.33 g/mol
Synonyms	3-(1,1-Dioxo-1λ⁶-thiomorpholin-4-yl)azepan-2-one; 2-Azepanone, 3-(1,1-dioxido-4-thiomorpholinyl)-; Wx-619126; Wx619126; Thiomorpholine dioxide azepanone derivative; 3-(Thiomorpholine 1,1-dioxide-4-yl)-2-azepanone
EINECS	Contact for details

Quality Control

Our 3-(1,1-Dioxido-4-Thiomorpholinyl)-2-Azepanone (Wx619126) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications. We support cGMP standards for advanced intermediate production where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.