Description

D-Lysine, 5-Fluoro-, (5S)- (9Ci) is a fluorinated derivative of the essential amino acid L-lysine, characterized by a fluorine atom at the 5-position and the (S)-configuration. This specific stereochemistry and halogenation make it a valuable non-natural amino acid building block for advanced research and development. It is primarily utilized by pharmaceutical researchers and biochemical manufacturers in the synthesis of novel peptides, proteomics studies, and the development of enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for metabolic and neurological targets.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a fluorinated lysine residue, altering peptide stability, bioavailability, and interaction with biological targets.
• Biochemical Research: Serves as a tool compound in enzyme kinetics studies, protein engineering, and investigating the role of specific amino acid residues in protein function.
• Proteomics & Labeling: Potential use in the design of activity-based probes or affinity tags for mass spectrometry-based proteomic analysis.
• Medicinal Chemistry: Employed to create analogs of bioactive peptides to enhance metabolic stability, receptor selectivity, or membrane permeability.

Basic Information

Product Name	D-Lysine, 5-Fluoro-, (5S)- (9Ci)
CAS No.	667464-73-5
Molecular Formula	C6H13FN2O2
Molecular Weight	164.18 g/mol
Synonyms	(2S)-2,6-Diamino-5-fluorohexanoic acid; 5-Fluoro-D-lysine; D-5-Fluorolysine; (S)-2,6-Diamino-5-fluorohexanoic acid; 5-Fluoro-DL-lysine (stereoisomer); Fluorolysine; 5-Fluoro-L-lysine enantiomer; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our D-Lysine, 5-Fluoro-, (5S)- (9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral assay, to ensure identity, strength, and composition. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% (5S)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.