Description

5-Chloro-2-[(3-Fluorobenzyl)Oxy]Benzaldehyde is a high-purity, multi-functional aromatic aldehyde building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both chloro and fluoro substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the creation of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and plant growth regulators, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and organocatalysts due to its aldehyde functionality and aromatic backbone.
• Material Science Precursor: Employed in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and conductive polymers.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	5-Chloro-2-[(3-Fluorobenzyl)Oxy]Benzaldehyde
CAS No.	667437-25-4
Molecular Formula	C14H10ClFO2
Molecular Weight	264.68 g/mol
Synonyms	5-Chloro-2-[(3-fluorophenyl)methoxy]benzaldehyde; 2-[(3-Fluorobenzyl)oxy]-5-chlorobenzaldehyde; 5-Chloro-2-(3-fluorobenzyloxy)benzaldehyde; Benzaldehyde, 5-chloro-2-[(3-fluorophenyl)methoxy]-; 667437-25-4
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-2-[(3-Fluorobenzyl)Oxy]Benzaldehyde is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for research and development. Our standard quality commitment includes HPLC purity ≥98% (area percentage), with detailed impurity profiling available. A Certificate of Analysis (COA) containing results for identity, assay, and related substances is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.