Description

1H-Inden-1-One, 3A,4,5,6,7,7A-Hexahydro-2-Methyl-, (3Ar,7Ar)-Rel- (9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex, saturated indanone structure. This compound is valued for its role as a critical chiral building block in the synthesis of complex organic molecules, particularly in medicinal chemistry. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing new active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including potential central nervous system (CNS) drugs.
• Asymmetric Synthesis: Utilized as a sophisticated starting material or intermediate in stereoselective organic synthesis to construct complex molecular architectures.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive compounds in academic and industrial R&D labs.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, including flavors, fragrances, and advanced materials.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial production for new chemical entities.

Basic Information

Product Name	1H-Inden-1-One, 3A,4,5,6,7,7A-Hexahydro-2-Methyl-, (3Ar,7Ar)-Rel- (9Ci)
CAS No.	663155-50-8
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	rel-(3aR,7aR)-2-Methyl-3a,4,5,6,7,7a-hexahydro-1H-inden-1-one; (3aR,7aR)-2-Methyloctahydroinden-1-one; 2-Methyl-1-indanone, hexahydro-, (3aR,7aR)-rel-; Hexahydro-2-methyl-1H-inden-1-one; Advanced Pharmaceutical Intermediate 663155-50-8
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management systems. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are supplied with each shipment. Our quality protocols are designed to support compliance with cGMP and ICH guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.