Description

(Z)-3-(4-Amino-3,5-Dimethylphenyl)Acrylonitrile CAS NO 661489-22-1 is a high-purity, functionalized acrylonitrile derivative featuring a stereospecific (Z)-configuration and a protected amino group. This compound serves as a versatile and critical pharmaceutical intermediate and organic building block for synthesizing complex molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted small-molecule drugs, particularly kinase inhibitors and other bioactive compounds.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators with specific stereochemistry.
• Advanced Material Monomer: Used in the research and development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research (R&D): Essential reagent for academic and industrial research in organic synthesis, medicinal chemistry, and material science.
• Dye and Pigment Intermediate: Serves as a precursor for synthesizing advanced colorants and functional dyes.

Basic Information

Product Name	(Z)-3-(4-Amino-3,5-Dimethylphenyl)Acrylonitrile
CAS No.	661489-22-1
Molecular Formula	C11H12N2
Molecular Weight	172.23 g/mol
Synonyms	(Z)-3-(4-Amino-3,5-dimethylphenyl)-2-propenenitrile; (Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile; 2-Propenenitrile, 3-(4-amino-3,5-dimethylphenyl)-, (Z)-; (Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile; (Z)-3-(4-Amino-3,5-dimethylphenyl)-2-propenenitrile; 661489-22-1; (Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile (CAS 661489-22-1)
EINECS	Contact for details

Quality Control

Our (Z)-3-(4-Amino-3,5-Dimethylphenyl)Acrylonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and stereochemical integrity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. The material is light-sensitive and easily oxidized; avoid exposure to air, moisture, and direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Isomeric Purity (Z-Isomer)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.