Description

1(2H)-Naphthalenone, Octahydro-6-Hydroxy-2-(1-Hydroxy-1-Methylethyl)-4A,8-Dimethyl- is a complex, polyfunctional decalin derivative of significant interest in advanced organic synthesis. This compound matters as a versatile chiral building block and key intermediate for the development of high-value specialty chemicals and active pharmaceutical ingredients (APIs). Industries requiring sophisticated molecular scaffolds, such as pharmaceutical R&D, agrochemical synthesis, and fragrance chemistry, will find this product essential for constructing complex, stereochemically defined structures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel therapeutic agents, particularly in steroid-like or terpenoid-based drug discovery programs.
• Agrochemical Synthesis: Serves as a precursor for developing advanced pesticides, herbicides, and plant growth regulators with specific stereochemical activity.
• Fragrance & Flavor Chemistry: Used in the creation of complex, long-lasting musk or woody amber base notes due to its stable, polycyclic structure.
• Advanced Material Research: Investigated as a monomer or additive for specialty polymers and liquid crystals, leveraging its rigid, functionalized backbone.
• Organic Synthesis Reagent: Employed in academic and industrial research laboratories for methodological studies in stereoselective synthesis and natural product total synthesis.
• Catalyst Ligand Precursor: Its multiple hydroxyl groups make it a candidate for developing chiral ligands used in asymmetric catalysis.

Basic Information

Item	Details
Product Name	1(2H)-Naphthalenone, Octahydro-6-Hydroxy-2-(1-Hydroxy-1-Methylethyl)-4A,8-Dimethyl-
CAS No.	660846-75-3
Molecular Formula	C15H28O3
Molecular Weight	256.38 g/mol
Synonyms	Octahydro-6-hydroxy-2-(1-hydroxy-1-methylethyl)-4a,8-dimethyl-1(2H)-naphthalenone; (4aS,6R,8aS)-6-Hydroxy-2-(2-hydroxypropan-2-yl)-4a,8-dimethyl-1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalen-1-one; Decahydro-6-hydroxy-2-(1-hydroxy-1-methylethyl)-4a,8-dimethyl-1(2H)-naphthalenone; Polyhydroxylated Decalone Derivative; Chiral Decalin Diol Ketone
EINECS	Contact for details

Quality Control

Our 1(2H)-Naphthalenone, Octahydro-6-Hydroxy-2-(1-Hydroxy-1-Methylethyl)-4A,8-Dimethyl- is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure consistent chemical identity and high purity suitable for sensitive synthetic applications. Comprehensive Certificates of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles are provided to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.