Description

6-Methylpyridine-3-Boronic Acid is a versatile and high-value boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to construct complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic structures.
• Material Science: Employed in the creation of organic electronic materials, ligands for catalysts, and metal-organic frameworks (MOFs).
• Suzuki-Miyaura Cross-Coupling: A pivotal reagent for palladium-catalyzed coupling reactions to form biaryl and other conjugated systems.
• Chemical Research & Development: Serves as a versatile synthon in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Ligand Preparation: Useful for synthesizing novel bidentate or tridentate ligands used in homogeneous catalysis.

Basic Information

Product Name	6-Methylpyridine-3-Boronic Acid
CAS No.	659742-21-9
Molecular Formula	C6H8BNO2
Molecular Weight	136.95 g/mol
Synonyms	(6-Methylpyridin-3-yl)boronic Acid; 3-Borono-6-methylpyridine; 6-Methyl-3-pyridineboronic Acid; 6-Methylnicotinoboronic Acid; 5-Borono-2-methylpyridine; 2-Methyl-5-pyridineboronic Acid; 6-Methylpyridine-3-boronic Acid Pinacol Ester (common derivative); 3-(6-Methylpyridyl)boronic Acid
EINECS	Contact for details

Quality Control

Our 6-Methylpyridine-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (typical grade)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.