Description

Boronic Acid, [4-[[(Tetrahydro-2H-Pyran-4-Yl)Amino]Carbonyl]Phenyl]- (9Ci) is a high-purity, functionalized boronic acid derivative designed for advanced synthetic chemistry. This compound is a critical building block in modern pharmaceutical research and development, enabling the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by medicinal chemists and process R&D scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reagent: Essential for constructing biaryl and heterobiaryl scaffolds, a fundamental transformation in medicinal chemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying biological pathways and protein interactions.
• Library Synthesis for High-Throughput Screening: Facilitates the rapid generation of diverse compound libraries for drug discovery campaigns.

Basic Information

Product Name	Boronic Acid, [4-[[(Tetrahydro-2H-Pyran-4-Yl)Amino]Carbonyl]Phenyl]- (9Ci)
CAS No.	657398-68-0
Molecular Formula	C14H18BNO4
Molecular Weight	275.11 g/mol
Synonyms	4-((Tetrahydro-2H-pyran-4-yl)carbamoyl)phenylboronic acid; [4-[[(Tetrahydro-2H-pyran-4-yl)amino]carbonyl]phenyl]boronic acid; 4-(N-Tetrahydropyran-4-yl)aminocarbonylphenylboronic acid; 4-Carbamoylphenylboronic acid tetrahydropyran-4-yl amide; B-[4-[[(Oxan-4-yl)amino]carbonyl]phenyl]boronic acid; 657398-68-0; Boronic acid, B-[4-[[(tetrahydro-2H-pyran-4-yl)amino]carbonyl]phenyl]-
EINECS	Contact for details

Quality Control

Every batch of our Boronic Acid, [4-[[(Tetrahydro-2H-Pyran-4-Yl)Amino]Carbonyl]Phenyl]- (9Ci) is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions and pharmaceutical applications. A detailed Certificate of Analysis (COA) specifying purity (typically ≥95% by HPLC), identity, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive (hygroscopic) and easily oxidized nature. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.