Description

(4-Ethyl-1-Piperazinyl)[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methanone is a high-value, advanced pharmaceutical intermediate featuring a piperazine core linked to a pinacol boronate ester. This compound matters as a critical building block in modern medicinal chemistry, enabling efficient cross-coupling reactions for the synthesis of complex molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates via Suzuki-Miyaura cross-coupling reactions.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Bioconjugation & Probe Development: Serves as a versatile handle for attaching fluorophores or other functional groups to target molecules for diagnostic and research applications.
• Chemical Biology: Employed in the development of chemical probes to study biological pathways and protein function.
• Material Science Research: Potential use as a monomer or functional unit in the synthesis of advanced organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines.

Basic Information

Product Name	(4-Ethyl-1-Piperazinyl)[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methanone
CAS No.	656239-39-3
Molecular Formula	C19H29BN2O3
Molecular Weight	344.26 g/mol
Synonyms	1-(4-Ethylpiperazin-1-yl)-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethanone; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl 4-ethylpiperazine; (4-Ethylpiperazinyl)[4-(pinacolatoboryl)phenyl]methanone; 4-Ethyl-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl]piperazine; Boronic ester piperazine derivative; 656239-39-3 (CAS Name); PINACOL (4-(4-ETHYLPIPERAZINE-1-CARBONYL)PHENYL)BORONATE
EINECS	Contact for details

Quality Control

Our (4-Ethyl-1-Piperazinyl)[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements. We support cGMP compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect purity and reactivity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.