Description

2',4'-Difluoro-3-(4-Fluorophenyl)Propiophenone is a high-purity fluorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. Its precise molecular architecture makes it a critical building block for the development of novel, high-value compounds. This product is essential for research and production facilities in the pharmaceutical and agrochemical sectors, particularly those focused on creating new active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the fluorine atoms contribute to improved biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or building block for developing specialty polymers and advanced organic materials with specific optical or electronic properties.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalytic systems used in asymmetric synthesis and other sophisticated chemical transformations.
• Academic and Industrial R&D: A valuable compound for methodological studies in fluorination chemistry and the exploration of new synthetic pathways in organic chemistry.

Basic Information

Product Name	2',4'-Difluoro-3-(4-Fluorophenyl)Propiophenone
CAS No.	654673-34-4
Molecular Formula	C15H11F3O
Molecular Weight	264.24 g/mol
Synonyms	1-(2,4-Difluorophenyl)-3-(4-fluorophenyl)propan-1-one; 3-(4-Fluorophenyl)-1-(2,4-difluorophenyl)propan-1-one; 2',4'-Difluoro-3-(p-fluorophenyl)propiophenone; 3-(4-Fluorophenyl)-2',4'-difluoropropiophenone; Propiophenone, 2',4'-difluoro-3-(4-fluorophenyl)-; DFPP Intermediate; Fluorinated Propiophenone Derivative
EINECS	Contact for details

Quality Control

Every batch of 2',4'-Difluoro-3-(4-Fluorophenyl)Propiophenone is manufactured and tested under a strict quality management system. We ensure compliance with rigorous internal specifications, which are designed to meet the exacting standards of our global pharmaceutical and fine chemical partners. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container must be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.