Description

(E)-4-(2-Phenoxyphenyl)-3-Buten-2-One is a high-purity, light-sensitive organic building block with the CAS number 652994-30-4. This compound serves as a critical intermediate in advanced organic synthesis, valued for its defined stereochemistry and reactive α,β-unsaturated ketone moiety. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its specific structure contributes to biological activity.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and organic electronic materials.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including asymmetric synthesis and cross-coupling reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrance and flavor compounds.

Basic Information

Product Name	(E)-4-(2-Phenoxyphenyl)-3-Buten-2-One
CAS No.	652994-30-4
Molecular Formula	C₁₆H₁₄O₂
Molecular Weight	238.28 g/mol
Synonyms	(E)-4-(2-Phenoxyphenyl)but-3-en-2-one; 4-(2-Phenoxyphenyl)-3-buten-2-one; 1-(2-Phenoxyphenyl)-3-buten-2-one; (E)-1-(2-Phenoxyphenyl)but-1-en-3-one; 2-Phenoxychalcone; 2-Phenoxybenzalacetone; (E)-4-(2-Phenoxyphenyl)-3-buten-2-one; 652994-30-4
EINECS	Contact for details

Quality Control

Our (E)-4-(2-Phenoxyphenyl)-3-Buten-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.