Description

6-Chloropyridine-2-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key synthon for constructing novel pyridine-based scaffolds in drug discovery and development programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides featuring chloropyridine motifs.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized bidentate ligands used in homogeneous catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and conductive polymers.
• Chemical Biology Probes: Useful for tagging and modifying biomolecules in proteomics and diagnostic assay development.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving diverse R&D and scale-up needs.

Basic Information

Product Name	6-Chloropyridine-2-Boronic Acid Pinacol Ester
CAS No.	652148-92-0
Molecular Formula	C11H15BClNO2
Molecular Weight	239.51 g/mol
Synonyms	2-Chloro-6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; (6-Chloropyridin-2-yl)boronic Acid Pinacol Ester; 6-Chloro-2-pyridineboronic Acid Pinacol Ester; 2-Chloro-6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pinacol (6-Chloropyridin-2-yl)boronate; 6-Chloro-2-pyridylboronic Acid Pinacol Ester; 652148-92-0; B-(6-Chloro-2-pyridinyl)boronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our 6-Chloropyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant regulatory frameworks, including REACH and ICH Q7 guidelines for active pharmaceutical ingredients (APIs).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.