Description

6-Bromopyridine-2-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. This compound matters because it enables precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. It is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries to create novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific halogenated heterocyclic structures.
• Material Science Research: Employed in the development of organic electronic materials, such as ligands for catalysts, OLED components, and conductive polymers.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester coupling partner to introduce the 6-bromo-2-pyridyl moiety into more complex molecular architectures.
• Chemical Biology & Medicinal Chemistry: Facilitates the rapid exploration of structure-activity relationships (SAR) in drug discovery programs through efficient library synthesis.
• Ligand Preparation: Useful for constructing sophisticated polydentate ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	6-Bromopyridine-2-Boronic Acid Pinacol Ester
CAS No.	651358-83-7
Molecular Formula	C11H15BBrNO2
Molecular Weight	268.96 g/mol
Synonyms	2-Bromo-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 6-Bromo-2-pyridineboronic acid pinacol ester; (6-Bromopyridin-2-yl)boronic acid pinacol ester; Pinacol (6-Bromopyridin-2-yl)boronate; 2-(6-Bromopyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Bromo-2-pyridylboronic acid pinacol ester; B-(6-Bromo-2-pyridinyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 6-Bromopyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when dispensing to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.