Description

3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Propan-1-Ol CAS NO 651030-57-8 is a high-value, protected boronic ester derivative featuring a terminal alcohol functional group. This bifunctional molecule is a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern organic synthesis. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and materials science sectors for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: The protected boronic ester group serves as a stable precursor for aryl boronic acids, enabling the formation of carbon-carbon bonds in the synthesis of complex organic molecules, including drug candidates.
• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Liquid Crystal and OLED Material Synthesis: Used in the development of advanced organic electronic materials, where its rigid biphenyl-like core and functional handles are incorporated into charge-transport or emissive layers.
• Agrochemical Active Ingredient Development: Employed in the research and synthesis of novel herbicides, fungicides, and plant growth regulators.
• Polymer Modification: The alcohol group allows for polymerization or grafting onto polymer backbones to create specialty polymers with tailored properties.
• Protecting Group Strategy: The dioxaborolane group protects the boronic acid functionality during multi-step syntheses, improving stability and yield.

Basic Information

Item	Information
Product Name	3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Propan-1-Ol
CAS No.	651030-57-8
Molecular Formula	C15H23BO3
Molecular Weight	262.15 g/mol
Synonyms	3-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propan-1-ol; 3-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1-propanol; 4-(3-Hydroxypropyl)phenylboronic acid pinacol ester; 3-(4-Pinacolatoborylphenyl)propan-1-ol; Pinacol 3-(4-Boronophenyl)propyl ether; B-[4-(3-Hydroxypropyl)phenyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of 3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Propan-1-Ol adheres to stringent GMP and ISO 9001 guidelines to ensure batch-to-batch consistency and high purity. Every lot undergoes comprehensive analytical characterization, including HPLC, NMR (1H, 13C, 11B), and GC/MS, to confirm identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) documenting all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis of the boronic ester.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.