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2-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Ethanol CAS NO 651030-56-7


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CAS No.:651030-56-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Ethanol is a high-purity, versatile boronic ester derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura coupling, which is fundamental for constructing complex molecular architectures. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and functional polymer development.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
  • Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides by introducing the phenyl ethanol boronate moiety into target molecules.
  • Material Science & OLED Development: Building block for synthesizing organic semiconductors, liquid crystals, and light-emitting materials for electronic displays.
  • Chemical Biology & Probe Development: Utilized in the creation of molecular probes and bioconjugates for diagnostic and research applications.
  • Polymer Chemistry: Monomer or co-monomer for producing specialty polymers with tailored properties.
  • Academic & Industrial R&D: Serves as a standard reagent in method development and scalable process chemistry for novel compound libraries.

Basic Information

Product Name 2-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Ethanol
CAS No. 651030-56-7
Molecular Formula C14H21BO3
Molecular Weight 248.13 g/mol
Synonyms 3-(2-Hydroxyethyl)phenylboronic acid pinacol ester; 2-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethan-1-ol; (3-(2-Hydroxyethyl)phenyl)boronic acid pinacol ester; 2-(3-Boronophenyl)ethanol pinacol ester; 651030-56-7; m-(2-Hydroxyethyl)phenylboronic acid pinacol ester; Pinacol [3-(2-hydroxyethyl)phenyl]boronate
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Quality Control

Every batch of 2-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Ethanol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including NMR, HPLC, and GC, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to minimize exposure to atmospheric moisture. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Assay (HPLC) ≥97.0%
Purity (GC) ≥96.0%
Water Content (KF) ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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