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2-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Ethanol CAS NO 651030-56-7
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CAS No.:651030-56-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Ethanol is a high-purity, versatile boronic ester derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura coupling, which is fundamental for constructing complex molecular architectures. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and functional polymer development.
Application
- Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
- Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides by introducing the phenyl ethanol boronate moiety into target molecules.
- Material Science & OLED Development: Building block for synthesizing organic semiconductors, liquid crystals, and light-emitting materials for electronic displays.
- Chemical Biology & Probe Development: Utilized in the creation of molecular probes and bioconjugates for diagnostic and research applications.
- Polymer Chemistry: Monomer or co-monomer for producing specialty polymers with tailored properties.
- Academic & Industrial R&D: Serves as a standard reagent in method development and scalable process chemistry for novel compound libraries.
Basic Information
| Product Name | 2-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Ethanol |
| CAS No. | 651030-56-7 |
| Molecular Formula | C14H21BO3 |
| Molecular Weight | 248.13 g/mol |
| Synonyms | 3-(2-Hydroxyethyl)phenylboronic acid pinacol ester; 2-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethan-1-ol; (3-(2-Hydroxyethyl)phenyl)boronic acid pinacol ester; 2-(3-Boronophenyl)ethanol pinacol ester; 651030-56-7; m-(2-Hydroxyethyl)phenylboronic acid pinacol ester; Pinacol [3-(2-hydroxyethyl)phenyl]boronate |
| EINECS | Contact for details |
Quality Control
Every batch of 2-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Ethanol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including NMR, HPLC, and GC, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to guarantee compliance with your research and production specifications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to minimize exposure to atmospheric moisture. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder or solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Assay (HPLC) | ≥97.0% |
| Purity (GC) | ≥96.0% |
| Water Content (KF) | ≤0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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