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2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Ethanol CAS NO 651030-55-6
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CAS No.:651030-55-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Ethanol is a high-value, advanced pharmaceutical intermediate and building block featuring a protected boronic ester functional group. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for forming carbon-carbon bonds. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science sectors for the development of novel active ingredients and functional polymers.
Application
- Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, especially in oncology and CNS therapeutic areas.
- Agrochemical Synthesis: Used in creating novel active ingredients for crop protection products with improved efficacy.
- Material Science: Precursor for organic electronic materials, including OLEDs and organic semiconductors.
- Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts.
- Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for target identification and validation.
- Polymer Chemistry: Enables the incorporation of aryl groups into polymer backbones to modify physical and electronic properties.
Basic Information
| Product Name | 2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Ethanol |
| CAS No. | 651030-55-6 |
| Molecular Formula | C14H21BO3 |
| Molecular Weight | 248.13 g/mol |
| Synonyms | 2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethanol; 4-(2-Hydroxyethyl)phenylboronic acid pinacol ester; 2-(4-(Pinacolboryl)phenyl)ethanol; 4-(2-Hydroxyethyl)benzeneboronic acid pinacol ester; 2-(p-Pinacolatoborylphenyl)ethanol; 651030-55-6; 4-(2-Hydroxyethyl)phenylboronic Acid, Pinacol Ester |
| EINECS | Contact for details |
Quality Control
Our production of 2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Ethanol adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are fully characterized, and Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment. We support development and scale-up with customized specifications to meet specific project requirements.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening containers to prevent hydrolysis of the boronic ester.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥97.0% |
| Water Content (KF) | ≤0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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