Description

4-[3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Morpholine is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. This compound is valued for its role in facilitating key carbon-carbon bond-forming reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key boronic ester precursor for creating biaryl and heterobiaryl structures central to many drug candidates.
• Pharmaceutical Intermediate: Used in the synthesis of potential therapeutic agents, including kinase inhibitors and other small molecule drugs.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Employed in the creation of organic electronic materials, such as those for OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Utilized in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Library Synthesis for Drug Discovery: Enables high-throughput parallel synthesis to generate diverse compound libraries for screening.

Basic Information

Product Name	4-[3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Morpholine
CAS No.	651014-89-0
Molecular Formula	C17H26BNO3
Molecular Weight	303.21 g/mol
Synonyms	3-Methyl-5-morpholinophenylboronic acid pinacol ester; 5-Morpholino-3-methylphenylboronic acid pinacol ester; 2-(3-Methyl-5-morpholin-4-ylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-[3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine; 651014-89-0; 3-Methyl-5-morpholinobenzeneboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of 4-[3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Morpholine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.