Description

Oxirane, 2-Ethyl-3-[2-(Phenylmethoxy)Ethyl]-, (2R,3R)-Rel-(-)- (9Ci) is a high-purity, chiral epoxide building block of significant interest in advanced organic synthesis. Its defined stereochemistry and reactive oxirane ring make it a critical intermediate for constructing complex molecules with precise three-dimensional architecture. This compound is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of potential drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the research and development of novel, stereospecific pesticides and herbicides where biological activity is enantiomer-dependent.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science Research: Employed in the creation of specialty polymers and advanced materials where the epoxide functionality enables cross-linking or further functionalization.
• Academic & Industrial Research: A valuable tool for methodological studies in organic chemistry, particularly in ring-opening reactions and stereochemistry investigations.

Basic Information

Item	Detail
Product Name	Oxirane, 2-Ethyl-3-[2-(Phenylmethoxy)Ethyl]-, (2R,3R)-Rel-(-)- (9Ci)
CAS No.	649343-06-6
Molecular Formula	C13H18O2
Molecular Weight	206.28 g/mol
Synonyms	(-)-2-Ethyl-3-(2-benzyloxyethyl)oxirane; rel-(2R,3R)-2-Ethyl-3-[2-(phenylmethoxy)ethyl]oxirane; (2R,3R)-2-Ethyl-3-(2-benzyloxyethyl)oxirane; Benzyl glycidyl ether derivative; Chiral ethyl-substituted oxirane; 2-Ethyl-3-(2-benzyloxyethyl)oxirane, (-)-; Oxirane, 2-ethyl-3-[2-(phenylmethoxy)ethyl]-, (2R,3R)-rel-
EINECS	Contact for details

Quality Control

Every batch of this chiral epoxide is produced and tested under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles, typically determined by advanced chromatographic methods (HPLC, GC). Our quality commitment ensures the reproducibility and reliability required for critical R&D and scale-up processes. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to the reactive epoxide moiety and potential sensitivity, it is recommended to store under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.